Advocin 2.5% solution for injection Advocin 2.5% Solution for Injection contains danofloxacin as the mesylate salt. It is a broad-spectrum fluoroquinolone antimicrobial that is active against a wide range of Gram-negative and Gram-positive bacteria, and mycoplasmas of veterinary importance. Advocin 2.5% Solution for Injection is very rapidly absorbed after intramuscular administration and has marked affinity for tissues of the lung and gastrointestinal tract. Licensed for use in cattle and pigs. Dosage & Administration Cattle Administer by the intramuscular or intravenous routes at a dosage rate of 1.25 mg danofloxacin/kg bodyweight (1 ml/20 kg bodyweight). Three treatments should be given at 24 hour intervals. Treatment may be extended up to an additional two days for animals that have not fully recovered after the initial three treatments. For treatment of cattle weighing more than 400 kg, divide the intramuscular dose so that no more than 20 ml are injected per site. Pigs Administer by intramuscular injection at a dosage rate of 1.25 mg danofloxacin/kg bodyweight (1 ml/20 kg bodyweight). Three treatments should be given at 24 hour intervals. For treatment of pigs weighing more than 100kg, divide the dose so that no more than 5ml are injected per site.
